Melillo Guido

Chi sono

  • Specialista in Cardiologia.
  • Direttore U.O.C . Cardiologia.
  • Opera per la Prevenzione e diagnosi clinica e strumentale  non invasiva delle patologie vascolari.

Attività scientifica

Pubblicazioni (MEDLINE – PUBMED)
 

1.    DI Vito L, Abeni D, Uras C, Magenta A, Ciarapica R, Capogrossi MC, Melillo G. Role of psoriasis on subclinical cardiovascular disease. Minerva Med. 2018 Jan 11.
2.    Magni G, La Rosa I, Melillo G, Abeni D, Hernandez H, Rosa G. Intracranial hemorrhage requiring surgery in neurosurgical patients given ketorolac: a case-control study within a cohort (2001-2010). Anesth Analg. 2013 Feb;116(2):443-7.
3.    Limana F, Esposito G, D'Arcangelo D, Di Carlo A, Romani S, Melillo G, Mangoni A, Bertolami C, Pompilio G, Germani A, Capogrossi MC. HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3. PLoS One. 2011;6(6):e19845. Epub 2011 Jun 22
4.    Cappuzzello C, Di Vito L, Melchionna R, Melillo G, Silvestri L, Cesareo E, Crea F, Liuzzo G, Facchiano A, Capogrossi MC, Napolitano M. Increase of plasma IL-9 and decrease of plasma IL-5, IL-7, and IFN-γ in patients with chronic heart failure. J Transl Med. 2011 Mar 21;9:28. PMID:21418620.
5.    Voellenkle C, van Rooij J, Cappuzzello C, Greco S, Arcelli D, Di Vito L, Melillo G, Rigolini R, Costa E, Crea F, Capogrossi MC, Napolitano M, Martelli F.  MicroRNA signatures in peripheral blood mononuclear cells of chronic heart failure patients. Physiol Genomics. 2010 Aug;42(3):420-6. Epub 2010 May 18. PubMed PMID: 20484156.
6.     De Falco E, Avitabile D, Totta P, Straino S, Spallotta F, Cencioni C, Torella AR, Rizzi R, Porcelli D, Zacheo A, Di Vito L, Pompilio G, Napolitano M, Melillo G, Capogrossi MC, Pesce M. Altered SDF-1-mediated differentiation of bone marrow-derived endothelial progenitor cells in diabetes mellitus. J Cell Mol Med. 2009 Sep;13(9B):3405-14. PubMed PMID: 20196780.
7.     Magni G, Rosa IL, Melillo G, Savio A, Rosa G. A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery. Anesth Analg. 2009 Aug;109(2):567-71. PubMed PMID: 19608833.
8.     Cappuzzello C, Napolitano M, Arcelli D, Melillo G, Melchionna R, Di Vito L, Carlini D, Silvestri L, Brugaletta S, Liuzzo G, Crea F, Capogrossi MC. Gene expression profiles in peripheral blood mononuclear cells of chronic heart failure patients. Physiol Genomics. 2009 Aug 7;38(3):233-40. Epub 2009 Mar 31. PubMed PMID: 19336532.
9.    Magni G, La Rosa I, Gimignani S, Melillo G, Imperiale C, Rosa G. Early postoperative complications after intracranial surgery: comparison between total intravenous and balanced anesthesia. J Neurosurg Anesthesiol. 2007, Oct;19(4):229-34. PubMed PMID: 17893573.
10.    Melillo G, Serino F, Cirielli C, Capogrossi MC. Gene therapy in peripheral artery disease. Curr Drug Targets Cardiovasc Haematol Disord. 2004 Sep;4(3):295-300. Review. PubMed PMID: 15379623.
11.     Cirielli C, Serino F, Straino S, Toietta G, Abeni D, Ventoruzzo G, Orlando G, Mazzanti P, Melillo G, Whickham TJ, Kovesdi I, Biglioli P, Gaetano C, Capogrossi MC. Adenovirus vectors targeting alphaV integrin or heparan sulfate receptors display different distribution of transgene activity after intramuscular injection. J Gene Med. 2004 Mar;6(3):309-16. PubMed PMID: 15026992.
12.     Romano Di Peppe S, Mangoni A, Zambruno G, Spinetti G, Melillo G, Napolitano M, Capogrossi MC. Adenovirus-mediated VEGF(165) gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice. Gene Ther. 2002 Oct;9(19):1271-7. PubMed PMID: 12224009.
13.     Melillo G, Capogrossi MC. [Perspectives of gene therapy in ischemic syndromes of the lower limbs]. Recenti Prog Med. 2001 Mar;92(3):180-3. Italian. PubMed PMID: 11320847.
14.     Melillo G, Capogrossi MC. Gene therapy with angiogenic factors for the treatment of ischemic diseases. Ital Heart J. 2000 Sep;1 Suppl 3:S59-60. PubMed PMID: 11003027.
15.     Palumbo R, Gaetano C, Melillo G, Toschi E, Remuzzi A, Capogrossi MC. Shear stress downregulation of platelet-derived growth factor receptor-beta and matrix metalloprotease-2 is associated with inhibition of smooth muscle cell invasion and migration. Circulation. 2000 Jul 11;102(2):225-30. PubMed PMID: 10889135.
16.     Toschi E, Rota R, Antonini A, Melillo G, Capogrossi MC. Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells. J Invest Dermatol. 2000 Jun;114(6):1188-94. PubMed PMID: 10844565.
17.    D'Arcangelo D, Facchiano F, Barlucchi LM, Melillo G, Illi B, Testolin L, Gaetano C, Capogrossi MC. Acidosis inhibits endothelial cell apoptosis and function and induces basic fibroblast growth factor and vascular endothelial growth factor expression. Circ Res. 2000 Feb 18;86(3):312-8. PubMed PMID: 10679483.
18.     Melillo G, Capogrossi M. [Prospects of gene therapy in the treatment of peripheral arterial diseases]. Minerva Cardioangiol. 1998 Sep;46(9):297-8. Italian. PubMed PMID: 10021851.
19.     Melillo G, Scoccianti M, Kovesdi I, Safi J Jr, Riccioni T, Capogrossi MC. Gene therapy for collateral vessel development. Cardiovasc Res. 1997 Sep;35(3):480-9. Review. PubMed PMID: 9415292.
20.     De Castro S, Pelliccia F, Cartoni D, Funaro S, Melillo G, Beni S, Magni G, Migliau G, Fedele F. Effects of angiotensin-converting enzyme inhibition on left ventricular geometric patterns in patients with essential hypertension. J Clin Pharmacol. 1996 Dec;36(12):1141-8. PubMed PMID: 9013371.
21.     Melillo G, Ruggieri MP, Magni G, Fragola PV, Antonini G, Vichi R, Cannata D, Fenici RR. Malignant cardiac involvement in a family with myotonic dystrophy. G Ital Cardiol. 1996 Aug;26(8):853-61. PubMed PMID: 8962420.
22.     Melillo G, Lima JA, Judd RM, Goldschmidt-Clermont PJ, Silverman HS. Intrinsic myocyte dysfunction and tyrosine kinase pathway activation underlie the impaired wall thickening of adjacent regions during postinfarct left ventricular remodeling. Circulation. 1996 Apr 1;93(7):1447-58. PubMed PMID: 8641035.
23.     Fenici RR, Covino M, Cellerino C, Di Lillo M, De Filippo MC, Melillo G. Magnetocardiographically-guided catheter ablation. J Interv Cardiol. 1995 Dec;8(6 Suppl):825-36. Review. PubMed PMID: 10159774.
24.     Bilato C, Pauly RR, Melillo G, Monticone R, Gorelick-Feldman D, Gluzband YA, Sollott SJ, Ziman B, Lakatta EG, Crow MT. Intracellular signaling pathways required for rat vascular smooth muscle cell migration. Interactions between basic fibroblast growth factor and platelet-derived growth factor. J Clin Invest. 1995 Oct;96(4):1905-15. PubMed PMID: 7560082; PubMed Central PMCID: PMC185827.
25.     Albanese A, Colosimo C, Bentivoglio AR, Fenici R, Melillo G, Colosimo C, Tonali P. Multiple system atrophy presenting as parkinsonism: clinical features and diagnostic criteria. J Neurol Neurosurg Psychiatry. 1995 Aug;59(2):144-51. PubMed PMID: 7629528; PubMed Central PMCID: PMC485989.
26.     Fenici R, Melillo G. Magnetocardiography: ventricular arrhythmias. Eur Heart J. 1993 Sep;14 Suppl E:53-60. PubMed PMID: 8223756.
27.     Fenici RR, Melillo G, Sponzilli C, Cavalieri E, Baldo E. Effects of posture, effort and psychophysiological activation on atrio-ventricular node and Kent bundle refractoriness. Funct Neurol. 1991 Jul-Sep;6(3):309-15. PubMed PMID: 1743548.
28.     Fenici RR, Melillo G. Biomagnetically localizable multipurpose catheter and method for MCG guided intracardiac electrophysiology, biopsy and ablation of cardiac arrhythmias. Int J Card Imaging. 1991;7(3-4):207-15. PubMed PMID: 1820402.
29.     Fenici RR, Melillo G, Masselli M. Clinical magnetocardiography. 10 years experience at the Catholic University. Int J Card Imaging. 1991;7(3-4):151-67. PubMed PMID: 1820397.
30.     Fenici RR, Melillo G. Biomagnetic study of cardiac arrhythmias. Clin Phys Physiol Meas. 1991;12 Suppl A:5-10. PubMed PMID: 1778053.

Capitoli su libri, rebiews inviate:
 

1.    Melillo G, Serino F, Cirielli C, Capogrossi MC. Gene therapy in peripheral artery disease. Current drug targets – Cardiovascular & Haematological disorders. 2004, 4, 295-300.
2.    Melillo G, Capogrossi MC. Gene therapy with angiogenic factors for the treatment of ischemic diseases. Ital Heart J. 2000 Sep;1 Suppl 3:S59-60.
3.    Melillo G., Napolitano M., Capogrossi M.C.: “La terapia genica con fattori angiogenici” in: “L’ulcera cutanea degli arti inferiori” G. Guarnera, M. Papi. 1a ed maggio 1998; 2a ed. nov. 2000
4.    Prospettive di terapia genica nel trattamento delle malattie dell’apparato cardiovascolare. Impegno Ospedaliero, 2-3/97: 5-10, 1997.
5.    Melillo G, Capogrossi MC. Sviluppo di tecniche di terapia genica per il trattamento delle ulcere ischemiche nelle arteriopatie obliteranti periferiche.  Chronica Dermatologica; 6: 169-175, 1996.
6.    Fenici R.R., Masselli M., Lopez L., Melillo G.: "High resolution electrocardiography and magnetocardiography". In: El-Sherif N, Turitto G (eds): High resolution electrocardiography. Mount Kisco, NY, Futura Publishing Co., Inc, 1992, pp. 147-172, 1992.
7.    Fenici R., Melillo G.: "La sindrome di preeccitazione cardiaca", in Zeppilli P., "Cardiologia dello Sport", Ed. C.E.S.I., 1990.
8.    Fenici R., Melillo G.: "Le indagini invasive in cardiologia dello Sport: nozioni generali e loro utilità",in Zeppilli P., "Cardiologia dello Sport", Ed. C.E.S.I., 1990.
9.    Fenici R.R., Masselli M., Lopez L., Melillo G.: "Clinical magnetocardiography. Localization of arrhythmogenic structures". in "Functional localization: a challenge for biomagnetism", S.N. Erné, G.L. Romani (eds.), World Scientific Co., pp. 102-118, 1989.
10.    Fenici R.R., Masselli M., Lopez L., Melillo G.: "Clinical value of magnetocardiography", in "Electrocardiography and cardiac drug therapy", V. Hombach, H.H. Hilger and H.L. Kennedy (eds.). Kluwer Academic Publishers, 239-258, 1989.

Abstracts:

oltre 50 comunicazioni a congressi nazionali ed internazionali.