• Patofisiologia della rigenerazione cutanea: analisi dei meccanismi e studio di potenziali terapie (finanziato dal Ministero della Salute, Ricerca Corrente)
• Phase II, multicenter, double blind, randomized controlled trial on “off the shelf” allogeneic Platelet Rich Plasma (PRP) to treat diabetic foot ulcers (coordinatrice UO IDI-IRCCS, finanziato dal Ministero della Salute, Ricerca Finalizzata)
• Anti-fibrotic therapeutic potential of histone deacetylase inhibitors (HDACi) for recessive dystrophic epidermolysis bullosa (RDEB) (Co-responsabile, finanziato da DEBRA International)
• MicroRNAs in dystrophic epidermolysis bullosa fibrosis: expression profiling, activity and therapeutic perspectives (Responsabile per IDI-IRCCS, finanziato da DEBRA International)

• 2012 – Ottiene l’Abilitazione Scientifica Nazionale a Professore di Prima Fascia per Biologia Applicata (settore concorsuale 5/F1)
• 2005 – Presenta le proprie ricerche alla Gordon Research Conference su Tissue Repair and Regeneration
• 2018 – Viene invitata dalla Fondazione Internazionale René Touraine a presentare la propria ricerca sul contrasto alla fibrosi cutanea nell’ambito dell’incontro annuale dal titolo “The role of the extracellular matrix in skin physiology and pathology”

• European Society for Dermatological Research (ESDR)
• Associazione Italiana per le Scienze degli Animali da Laboratorio (AISAL)

Pubblicazioni

• 2024 Nov 12 - Scientific reports - The healing process of diabetic ulcers correlates with changes in the cutaneous microbiota.
• 2024 Sep 18 - The British journal of dermatology - Histone deacetylase inhibition mitigates fibrosis-driven disease progression in recessive dystrophic epidermolysis bullosa.
• 2024 Jul - The Journal of investigative dermatology - Gamma-Secretase Inhibitors Downregulate the Profibrotic NOTCH Signaling Pathway in Recessive Dystrophic Epidermolysis Bullosa.
• 2022 Sep 2 - International journal of molecular sciences - Is Melanoma Progression Affected by Thyroid Diseases?
• 2022 - Frontiers in bioengineering and biotechnology - Innovative Cell and Platelet Rich Plasma Therapies for Diabetic Foot Ulcer Treatment: The Allogeneic Approach.
• 2020 Jun - Journal of dermatological science - Dysregulation of microRNA expression in diabetic skin.
• 2019 Aug - Matrix biology : journal of the International Society for Matrix Biology - Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosa.
• 2019 - ALTEX - Non-animal models in dermatological research.
• 2018 Dec - Reviews in endocrine & metabolic disorders - Thyroid diseases and skin autoimmunity.
• 2018 Apr - Journal of dermatological science - Mice over-expressing placenta growth factor in the skin exhibit increased vascularization and vessel permeability independently of VEGF-A.
• 2017 - Frontiers in endocrinology - Vitiligo and Autoimmune Thyroid Disorders.
• 2017 Jul - The American journal of pathology - Pathomechanisms of Altered Wound Healing in Recessive Dystrophic Epidermolysis Bullosa.
• 2017 Nov - Matrix biology : journal of the International Society for Matrix Biology - Stromal microenvironment in type VII collagen-deficient skin: The ground for squamous cell carcinoma development.
• 2016 Apr - The Journal of investigative dermatology - Epigenetic Control of Skin Re-Epithelialization: the NF-kB/JMJD3 Connection.
• 2015 Dec - The FEBS journal - The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.
• 2015 Nov - The Journal of investigative dermatology - Interleukin-22 Promotes Wound Repair in Diabetes by Improving Keratinocyte Pro-Healing Functions.
• 2014 Aug 1 - Human molecular genetics - Monozygotic twins discordant for recessive dystrophic epidermolysis bullosa phenotype highlight the role of TGF-β signalling in modifying disease severity.
• 2013 Jul-Aug - Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - Diabetes impairs adipose tissue-derived stem cell function and efficiency in promoting wound healing.
• 2012 Sep - Journal of cutaneous pathology - Expression of vascular endothelial growth factor-C in primary cutaneous melanoma predicts sentinel lymph node positivity.
• 2012 Jul-Aug - European journal of dermatology : EJD - The atypical retinoid E-3-(3'-Adamantan-1-yl-4'-methoxybiphenyl-4-yl)-2-propenoic acid (ST1898) displays comedolytic activity in the rhino mouse model.
• 2012 Jan 24 - Proceedings of the National Academy of Sciences of the United States of America - p63-microRNA feedback in keratinocyte senescence.
• 2011 Sep - The Journal of investigative dermatology - Impaired keratinocyte proliferative and clonogenic potential in transgenic mice overexpressing 14-3-3σ in the epidermis.
• 2009 Dec - The Journal of clinical investigation - Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling.
• 2010 Jan - The Journal of investigative dermatology - TSH receptor and thyroid-specific gene expression in human skin.
• 2008 Sep 15 - Journal of cell science - HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration.
• 2007 - Progress in histochemistry and cytochemistry - Regulation of angiogenesis: wound healing as a model.
• 2007 Jun 11 - The Journal of experimental medicine - Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.
• 2006 Oct - The American journal of pathology - Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
• 2006 Jan - Journal of dermatological science - The placenta growth factor in skin angiogenesis.
• 2003 Aug 15 - Cancer - Vascular endothelial growth factor-C expression correlates with lymph node localization of human melanoma metastases.
• 2002 Nov-Dec - European journal of dermatology : EJD - Molecular control of physiological skin angiogenesis.
• 2002 Jun 15 - Journal of cell science - Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeability.